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Vinorelbine Side Effects

It is common for people who are receiving vinorelbine to develop some type of side effect during treatment. Studies have shown that some of the most commonly reported problems include nausea, low levels of white blood cells, and anemia. Because some side effects of vinorelbine can lead to potentially dangerous problems, seek medical treatment if you develop fever, severe constipation, or difficulty breathing.

An Introduction to Side Effects of Vinorelbine

As with any chemotherapy medicine, vinorelbine (Navelbine®) can cause side effects. In fact, most people will experience some type of reaction to this drug, and some problems can be quite significant. Talk to your healthcare provider about ways to prevent or lessen reactions to this medicine.
(This article covers many, but not all, of the possible side effects with vinorelbine. Your healthcare provider can discuss a more complete list with you.)

Serious Vinorelbine Side Effects

Some vinorelbine side effects are potentially serious and should be reported to your healthcare provider immediately. These potential reactions include but are not limited to:
  • Signs of infection, such as:
    • Fever
    • Chills
    • Aches and pains
    • Sore throat
    • Cough
    • Nausea
    • Vomiting
  • Redness, swelling, blisters, pain, or leakage of fluid around your injection site (the site where you receive your dose)
  • Severe constipation
  • Cough or shortness of breath
  • Sores in your mouth or throat (see Mouth and Gum Problems During Chemotherapy)
  • Signs of liver problems, such as:
    • Yellowing of the skin or whites of the eyes (jaundice)
    • Dark urine
    • Extreme tiredness
    • Pain on the right side of the abdomen (stomach)
  • Chest pain
  • Warmth, redness, pain, or swelling over one area of an arm or leg
  • Changes in how well you hear
  • Muscle weakness that causes difficulty moving or walking
  • Low blood pressure (hypotension) or high blood pressure (hypertension)
  • A fast heartbeat (tachycardia)
  • Severe or persistent nausea and vomiting
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling, especially of the mouth, lips, or throat
    • Wheezing
    • Difficulty breathing or swallowing.
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Vinorelbine Drug Information

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