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What Are Histrelin Implants Used For?

Histrelin implants are prescribed for treating advanced prostate cancer in adult men and puberty that has started too early in children (central precocious puberty). This medicine works by decreasing the amount of testosterone produced in the testes and the amount of estrogen produced in the ovaries. Some off-label uses for histrelin implants include the treatment of other types of cancer.

An Overview of Uses for Histrelin Implants

Histrelin implants (Supprelin® LA, Vantas®) belong to a class of medications called gonadotropin-releasing hormone (GnRH) agonists, sometimes also called luteinizing hormone-releasing hormone (LH-RH) agonists. It is a long-acting implant that is inserted just beneath the skin of the upper arm. Once inserted, a histrelin implant continuously releases the medication histrelin into the body for 12 months.
Histrelin implants are approved to treat:

Using Histrelin Implants for Advanced Prostate Cancer

Histrelin implants are approved for the palliative treatment of advanced prostate cancer. Prostate cancer is considered advanced when it has spread to other areas of the body, such as the bones, bladder, or rectum. Prostate cancer that has spread beyond the prostate is also called metastatic prostate cancer.
The goal of palliative cancer treatment is to ease the symptoms of cancer and improve quality of life. Histrelin implants can help slow down the growth of prostate cancer cells and relieve symptoms such as pain. However, it is not a cure for prostate cancer.
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Histrelin Implant Information

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