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Folotyn Overdose

Complications such as bleeding problems or seizures may occur if someone receives too much Folotyn (pralatrexate). However, the specific effects will depend on how much of the drug was used and other factors. Treating this type of overdose may involve administering a certain medication that can help minimize and reverse the overdose effects.

Can You Receive Too Much Folotyn?

Folotyn® (pralatrexate) is a prescription medication used to treat peripheral T-cell lymphoma, a cancer of the lymphatic system, usually after other medicines have been tried and failed. As with most medicines, it is possible to use too much Folotyn. The specific effects of an overdose can vary, depending on a number of factors, including the Folotyn dosage and whether it was combined with any other medications or substances.

Effects of an Overdose

Symptoms of an overdose with Folotyn may include:
  • Dangerously low blood cell counts, which could cause:
    • Infections
    • Bleeding
    • Serious anemia
  • Mouth sores
  • Nausea
  • Vomiting
  • Fever
  • Fatigue
  • Seizures.

Treating a Folotyn Overdose

Treatment for this type of overdose usually involves the use of a medicine known as leucovorin. Leucovorin can limit and help reverse some of the Folotyn overdose effects. Treatment will also likely involve supportive care, which consists of treating the symptoms that occur as a result of the overdose. Supportive care may include intravenous (IV) fluids or certain medications to treat seizures if they occur.
It is important that you seek medical attention immediately if you believe that you have received too much Folotyn.
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Folotyn Medication Information

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