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Etoposide Phosphate Side Effects

Clinical trials on etoposide phosphate have shown that side effects are likely to occur in most people undergoing chemotherapy treatment with this drug. Some of the most commonly reported problems include vomiting, hair loss, and low levels of blood cells. It is also important to seek medical treatment if you develop a fever, vision loss, or other serious problems.

An Introduction to Side Effects of Etoposide Phosphate

As with any chemotherapy medicine, etoposide phosphate (Etopophos®) can cause side effects, some of which can be quite significant. In fact, most people will experience some type of reaction to this drug. Talk to your healthcare provider about ways to prevent or lessen reactions to this medicine.
(This article covers many, but not all, of the possible side effects with etoposide phosphate. Your healthcare provider can discuss a more complete list with you.)

Serious Etoposide Phosphate Side Effects

Some side effects of etoposide phosphate are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Signs of an infection, such as:
    • Fever
    • Chills
    • Aches and pains
    • Sore throat
    • Painful urination
  • Swelling, redness, or pain in an arm or leg
  • Signs of anemia, such as:
    • Extreme weakness or fatigue
    • Pale skin
    • Shortness of breath
    • Dizziness
  • Unusual bleeding or bruising
  • Black, tarry stools or blood in the urine
  • Swelling, sores, ulcers, or blisters in the mouth or throat
  • Swelling, burning, pain, redness, or leakage of fluid around your infusion site (the site where you receive your dose)
  • A new or worsening cough
  • Total or partial loss of vision
  • Signs of liver problems, such as:
    • Yellowing of the skin or whites of the eyes (jaundice)
    • Dark urine
    • Upper-right abdominal (stomach) pain
  • Persistent diarrhea, nausea, or vomiting
  • Burning, tingling, numbness, or other unusual sensations in the arms, hands, legs, or feet
  • Signs of an allergic reaction, especially while receiving your infusion, such as:
    • Chills
    • Cold shivers
    • Fever
    • A fast heart rate (tachycardia)
    • A rash
    • Hives
    • Itching
    • Swelling of the mouth, tongue, face, lips, or throat
    • Difficulty breathing or swallowing
    • A feeling of tightness in the throat
    • Coughing
    • Sweating
    • Dizziness or fainting
    • Nausea and vomiting
  • Signs of dehydration, such as:
    • Extreme thirst
    • Dry mouth and lips
    • Lightheadedness
    • Less frequent urination.
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Etoposide Phosphate Drug Information

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