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Etoposide Phosphate Dosage

The guidelines for calculating the appropriate etoposide phosphate dosage are highly individualized and will largely depend on a person's height and weight. Other factors that may affect the amount include the type of cancer being treated and other medications being taken. Etoposide phosphate is injected slowly into a vein by a healthcare provider in a healthcare setting.

An Introduction to Your Dosage of Etoposide Phosphate

The dose of etoposide phosphate (Etopophos®) your healthcare provider recommends will vary, depending on a number of factors, including:
  • Your height and weight
  • The type of cancer being treated
  • How you respond to the medication
  • Other medications you are taking
  • Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

What Is the Recommended Etoposide Phosphate Dose for Small Cell Lung Cancer?

Like many chemotherapy medicines, etoposide phosphate dosing is based on body surface area, which is normally calculated using your height and weight. Doses based on body surface area are expressed as milligrams per meters squared (mg per m2).
In addition, etoposide phosphate contains a salt form of the medication etoposide (Toposar®). Doses of etoposide phosphate are usually expressed as the desired etoposide dose, rather than the etoposide phosphate dose. This means that a healthcare provider will normally write an order to give an etoposide phosphate dose equivalent to a certain amount of etoposide. The pharmacist will then determine how much etoposide phosphate should be given.
The usual dose of etoposide phosphate for treating small cell lung cancer is highly individualized and can range from the equivalent to 35 mg per m2 of etoposide once a day for four days to a dose equivalent to 50 mg per m2 of etoposide once a day for five days. People with kidney or liver disease are normally given lower amounts.
After receiving etoposide phosphate for four or five days, you will be given a break in treatment to allow your body to recover from any side effects. The treatment and break period make up a cycle of treatment. Etoposide phosphate treatment cycles are normally repeated every three to four weeks. Your healthcare provider will tell you how many treatment cycles you need.
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Etoposide Phosphate Drug Information

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