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BiCNU Dosage

BiCNU is given as a slow injection into a vein no more often than every six weeks. The dosage of BiCNU you receive will depend on a number of things, such as your height and weight, and how well you respond to the drug. This medicine can cause a significant drop in blood cell counts, which will be closely monitored on a weekly basis.

An Introduction to Dosing With BiCNU

The dosage of BiCNU® (carmustine) your healthcare provider recommends will vary, depending on a number of factors, including:
  • Your height and weight
  • How you respond to and tolerate it
  • Other medications you are taking.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

What Is the Recommended BiCNU Dosage?

Like many chemotherapy medicines, BiCNU dosing is based on body surface area, which is normally calculated using your height and weight. Doses based on body surface area are written as milligrams per meter squared (mg per m2).
The initial recommended dosage of BiCNU, when used alone, is usually 150 to 200 mg per m2 every six weeks. The dose may be given on one day as a single dose, or divided up as 75 to 100 mg per m2 on two consecutive days. People who are receiving other chemotherapy medicines may need lower doses.
BiCNU can cause a significant decrease in blood cells. Your healthcare provider will monitor your blood cell counts weekly after each BiCNU dose and adjust your next dosage based on how low your blood cell counts drop.
BiCNU is given no more often than every six weeks, as it usually takes blood cell counts about that long to return to normal. However, your healthcare provider may recommend a longer break in treatment if your blood cell counts remain too low.
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