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Abstral Side Effects

Constipation, nausea, and headaches are the most common side effects reported with Abstral. Other possible problems, occurring in at least 1 percent of people taking the drug, include blurred vision, heartburn, and weakness. Although most side effects do not require medical attention, you should contact your healthcare provider immediately if you experience severe constipation, hallucinations, or difficulty breathing.

An Introduction to Abstral Side Effects

Just like any medicine, Abstral® (fentanyl sublingual tablets) can cause side effects. However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Abstral. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects With Abstral

Abstral has been studied thoroughly in clinical trials. In these studies, the side effects that occurred in a group of people taking the drug were carefully recorded. In all the studies, long-acting opioid narcotics were used in addition to Abstral. Therefore, it can be difficult to know whether the side effects observed were due to Abstral or the other opioid medication.
In clinical studies, the most common Abstral side effects included:
  • Nausea -- in up to 6.0 percent of people
  • Constipation -- up to 4.8 percent
  • Headaches -- up to 3.0 percent
  • Drowsiness -- up to 4.4 percent
  • Dizziness -- up to 2.2 percent
  • Redness, swelling, and inflammation of the lining of the mouth -- up to 1.8 percent
  • Tiredness (fatigue) -- up to 1.8 percent
  • Dry mouth -- up to 1.8 percent
  • A bad taste in the mouth -- up to 1.2 percent
  • Excessive sweating -- up to 1.2 percent.
Other problems that occurred in at least 1 percent of people given Abstral in clinical trials included:
  • A fast or slow heart rate
  • Blurred vision
  • Abdominal (stomach) pain
  • Sores or ulcers on the lining of the mouth, lips, or tongue
  • Shortness of breath
  • Indigestion or heartburn
  • Vomiting
  • Delayed stomach emptying
  • Weakness or lack of energy
  • General feelings of discomfort
  • Accidental overdose
  • Decreased or loss of appetite
  • Memory problems
  • Reduced sense of touch
  • Abnormal sense of smell
  • Shakiness (tremors)
  • Problems sleeping
  • Erectile dysfunction (ED) or impotence
  • Throat pain or tightness
  • Itching
  • Rash
  • Night sweats
  • Decreased blood pressure (hypotension).
Alternative Therapies for Pain Management

Abstral Medication Information

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