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Zortress Uses

How Does This Medicine Work?

Zortress works to prevent transplant rejection by weakening the immune system. When certain white blood cells, called lymphocytes, encounter a foreign material, they change into an active form, and begin to rapidly reproduce so there are more of them available to fight the invading substance. Zortress blocks the activation and rapid reproduction of the lymphocytes, thus preventing an immune response against the newly transplanted organ.

Is It Safe for Children?

This drug is not approved for use in individuals younger than 18 years of age. It is unknown if the medicine is safe or effective for use in younger people, as it has not been adequately studied in this age group. Talk to your child's healthcare provider about the risks and benefits of using Zortress in children.

Can Older Adults Use Zortress?

Zortress may be used in older adults. Dosing adjustments are not needed based on age alone. However, some older adults may be more sensitive to the effects of this medication, and therefore may need to be monitored more closely.

Off-Label Uses for Zortress

On occasion, your healthcare provider may recommend this medicine for something other than preventing kidney transplant rejection. This is called an "off-label" use. At this time, there are no well-accepted off-label uses for Zortress.
Zortress has been associated with an increased risk for death from infection when used in people who have had a heart transplant. Therefore, the off-label use of Zortress to prevent organ rejection following a heart transplant is not recommended.
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Zortress Medication Information

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