Zometa Drug Interactions (Cont.)

Zometa Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Zometa is combined with any of the drugs listed above.
 
Aminoglycosides
Taking Zometa with an aminoglycoside antibiotic can increase the risk of low blood calcium (hypocalcemia) and kidney damage. Talk to your healthcare provider before taking these medications together.
 
Diuretics
Combining Zometa with a diuretic may increase the risk of kidney damage. It is very important that you are adequately hydrated before your Zometa dose, particularly if you are taking a diuretic. If you are not adequately hydrated, your healthcare provider may need to give you IV fluids before your Zometa dose. Also, some diuretics (but not all) can increase the risk of low blood calcium with Zometa. Talk with your healthcare provider before taking Zometa with a diuretic.
 
Nonsteroidal Anti-Inflammatory Drugs (NSAIDS)
Combining an NSAID with Zometa may increase the risk of kidney damage, particularly in people who already have kidney disease. Talk with your healthcare provider before combining Zometa with an NSAID.
 
Vancomycin (Vancocin)
Taking Zometa with vancomycin can increase your risk of kidney damage. Talk with your healthcare provider before taking these medications together, particularly if you already have kidney disease.
 

Final Thoughts on Zometa Drug Interactions

It is possible that not all Zometa drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions that may apply to you.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;