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Generic Zometa

You can now buy Zometa (zoledronic acid) in generic form. It comes in one strength. The FDA has assigned an "AP" rating to this product, which means that it is considered equivalent to the brand-name version. However, generic Zometa is allowed to have different inactive ingredients (such as fillers or dyes), which may cause problems for people with certain allergies or sensitivities.

Generic Zometa: An Overview

Zometa® (zoledronic acid) is a medication approved to treat high calcium or to prevent bone problems caused by cancer. It is available by prescription only and is given by IV. Zometa belongs to a group of medications known as bisphosphonates and is manufactured by Novartis Pharmaceuticals. It is available in generic form.

Availability of Generic Zometa

Generic Zometa is available in one strength: Zoledronic acid 4 mg, in 5-mL vials. It is made by manufacturers such as:
  • Dr. Reddy’s Laboratories
  • JHP Pharmaceuticals, Inc.
  • Sagent Pharmaceuticals.
Zometa 4 mg in 100-mL ready-to-use bottles is not yet available in generic form.

Is Generic Zoledronic Acid as Good as Zometa?

All generic medications must undergo certain tests to compare them to brand-name medications. The U.S. Food and Drug Administration (FDA) then looks at these tests to decide if the generics are equivalent to the brand-name medications and assigns a rating to each one.
An “AP” rating means that the FDA has determined that a generic medication is equivalent to a brand-name medication. All of the generic Zometa versions currently available have an "AP" rating, meaning they should be equivalent to the brand-name product.
However, generic medications are allowed to have different inactive ingredients than the brand-name medication. This might include fillers, dyes, or other ingredients that may cause problems for people with allergies or sensitivities.
Also, note that zoledronic acid 5 mg per 100 mL is not equivalent to Zometa. This product is a generic version of Reclast®, a medication used to treat Paget’s disease.
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