Zofran ODT 4 mg Orally Disintegrating Tablets

Before radiation therapy, surgery, or chemotherapy, your healthcare provider may give you the prescription medicine Zofran® (ondansetron hydrochloride) to prevent nausea and vomiting. Zofran comes in several different forms and strengths, including:
 
  • 4 mg Zofran tablets
  • 8 mg Zofran tablets
  • 4 mg Zofran ODTs (orally disintegrating tablets)
  • 8 mg Zofran ODTs (orally disintegrating tablets)
  • Zofran oral solution 5 mg per 5 mL (one teaspoon)
  • Zofran injection.
     
Your Zofran dosage can be taken with or without food. If water or food makes you sick to your stomach or you experience nausea after eating or drinking, the orally disintegrating tablets may be especially useful, as they do not require any water (they dissolve in your mouth).
 
The oral solution or orally disintegrating tablets may be especially useful for children (both are strawberry-flavored). For children ages 4 to 11, the recommended dosage is one 4 mg orally disintegrating tablet three times daily.
 
(Click Zofran Dosage to find dosing guidelines for both adults and children, for warnings concerning the safety of this drug, and for information on what your healthcare provider will consider before making a dosage recommendation for your situation.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;