Zofran and Depression (Cont.)

Zofran and Depression: What Should You Look For?

Depression is extremely common in society today. In fact, in any given one-year period, 9.5 percent of the population (about 18.8 million American adults) has depression. Therefore, knowing the symptoms of depression can be helpful.
 
Possible depression symptoms may include:
 
  • Persistent sad, anxious, or "empty" mood
  • Feelings of hopelessness and pessimism
  • Feelings of guilt, worthlessness, and helplessness
  • Loss of interest or pleasure in hobbies and activities that were once enjoyed, including sex
  • Decreased energy; fatigue; feeling "slowed down"
  • Difficulty concentrating, remembering, and making decisions
  • Insomnia, early-morning awakening, or oversleeping
  • Appetite and/or weight loss, or overeating and weight gain
  • Thoughts of death or suicide and suicide attempts
  • Restlessness and irritability
  • Persistent physical symptoms, such as headaches, digestive disorders, and chronic pain, that do not respond to treatment.
     
Keep in mind that there are other conditions that can share similar symptoms with depression.
 

Zofran and Depression: A Summary

For people taking Zofran, depression does not appear to be a side effect. However, depression is common in the general population, and is common in people diagnosed with cancer. Therefore, for people with cancer who are taking Zofran, it is important to understand the signs and symptoms of depression. If you have any possible symptoms of depression -- or if something "just does not seem right," you should talk to your healthcare provider. Your healthcare provider will be able to diagnose and treat the problem.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;