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Clinical Effects of Zevalin

In clinical trials, Zevalin has been shown to decrease the risk of disease progression in people with non-Hodgkin's lymphoma. In these studies, people who received Zevalin after responding to first-line chemotherapy had a 54 percent decreased risk of their cancer progressing further, compared to people who did not receive any additional treatment.
In another study, 83 percent of people with relapsed or refractory non-Hodgkin's lymphoma responded to treatment with Zevalin in combination with rituximab. By comparison, only 55 percent of people responded to rituximab treatment alone.

When and How to Receive It

Some general considerations to keep in mind during treatment with Zevalin include the following:
  • This medication comes as a liquid that is given as an injection into a vein (an intravenous, or IV, injection) over a 10-minute period.
  • Zevalin is part of a treatment regimen that includes rituximab. It is normally given as a single dose within four hours after receiving a second dose of rituximab.
  • The injection will be given by a healthcare provider in a healthcare setting, such as a hospital or clinic.
  • For the medication to work properly, it must be used as prescribed. It is important to keep your appointment to receive your Zevalin dose.

Dosing Information

The dose of Zevalin your healthcare provider recommends will vary, depending on your platelet count and your weight. As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
(Click Zevalin Dosage for more information.)
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Zevalin Medication Information

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