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When and How to Use It

Some general considerations to keep in mind during treatment with Xgeva include the following:
  • The medication comes in an injectable form. It is injected once every four weeks just under the skin (subcutaneously) in the lower abdomen (stomach), upper arm, or upper thigh.
  • In most cases, your healthcare provider will administer the injections; the product is not specifically designed for at-home use.
  • You might need to take calcium and vitamin D while using Xgeva, to prevent dangerously low blood calcium levels (a potential side effect of the drug). Check with your healthcare provider first, however, as people with cancer sometimes have very high blood calcium levels.
  • For the medication to work properly, it must be used as prescribed.

Dosing Information

There is only one recommended dose of Xgeva, regardless of your age, weight, or other medical conditions. As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
(Click Xgeva Dosage for more information.)

Side Effects of Xgeva

Just like any medicine, Xgeva can cause side effects. However, not everyone who uses the medicine will have problems. In fact, most people tolerate it quite well.
If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
Some of the most common Xgeva side effects include but are not limited to:
  • General weakness and/or fatigue
  • Low phosphate levels in the blood (as measured by a blood test)
  • Nausea.
(Click Xgeva Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
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Xgeva Injection Information

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