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Waldenström's Macroglobulinemia

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Waldenström's macroglobulinemia patients who are taking sildenafil (Viagra®) for treatment of erectile dysfunction showed improvement in Waldenström's macroglobulinemia symptoms. Clinical trials are planned.
 
In order for Waldenström's macroglobulinemia research to be conducted, volunteers are needed. Patients who join Waldenström's macroglobulinemia research studies will have the first chance to benefit from new treatments that have shown promise in earlier research. Patients who volunteer will also make an important contribution to medical science by helping doctors learn more about Waldenström's macroglobulinemia. Although Waldenström's macroglobulinemia research trials may pose some risks, researchers take careful steps to protect their patients.
 

Waldenström's Macroglobulinemia: Summary of Key Points

Key information about Waldenström's macroglobulinemia includes the following:
 
  • Waldenström's macroglobulinemia is a rare type of slow-growing, non-Hodgkin's lymphoma (cancer that begins in the cells of the immune system). It causes overproduction of a protein called monoclonal macroglobulin (IgM) antibody.
 
  • Waldenström's macroglobulinemia symptoms include weakness, swollen lymph nodes, severe fatigue, nosebleeds, weight loss, and visual and neurological problems. Some patients do not have symptoms.
 
  • Tests and procedures doctors may use to diagnose Waldenström's macroglobulinemia may include blood tests, a bone marrow biopsy, a CT scan, and others.
 
  • Treatment options for Waldenström's macroglobulinemia in patients with symptoms may include plasmapheresis, chemotherapy, and biological therapy.
 
  • People with Waldenström's macroglobulinemia are often encouraged to participate in clinical trials in which new treatments are studied.
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