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Vemurafenib Side Effects

If you are taking vemurafenib, you may develop nausea, diarrhea, or joint pain -- these are just a few of the commonly reported problems with this medication. This medicine can also cause potentially serious complications, such as allergic reactions, skin changes, or liver problems. If you experience any of these or other potentially serious side effects with vemurafenib, contact your healthcare provider right away.

An Introduction to Side Effects of Vemurafenib

Just like any medicine, vemurafenib (Zelboraf™) can cause side effects. Like most cancer medications, the side effects can be significant. Although not everyone who takes this medication will have problems, many people will experience some type of side effect during vemurafenib treatment. Talk to your healthcare provider about ways to manage these side effects.
(This article covers many, but not all, of the possible side effects with vemurafenib. Your healthcare provider can discuss a more complete list with you.)

Serious Vemurafenib Side Effects

Some side effects of vemurafenib are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling, especially of the mouth, lips, or throat
    • Wheezing
    • Difficulty breathing or swallowing
  • Any skin changes, such as:
    • Skin bumps or growths
    • Sores that bleed or do not heal
    • Changes in the size or color of moles
    • New warts
  • Redness, tenderness, or peeling of the palms of the hands, soles of the feet, or any other area of the skin
  • Signs of liver problems, such as:
    • Yellowing of the skin or whites of the eyes (jaundice)
    • Dark urine
    • Extreme tiredness
    • Nausea and vomiting
    • Pain on the upper-right area of the abdomen (stomach)
  • Lightheadedness, dizziness, or fainting
  • An irregular heartbeat
  • A sunburn
  • Eye pain or redness, blurry vision, or sensitivity to light.
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Vemurafenib Drug Information

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