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Toremifene Side Effects

Common Side Effects

Toremifene has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking the drug were documented and then compared to those that occurred in a similar group of people taking a different breast cancer medication called tamoxifen (Nolvadex®, Soltamox®). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared with the other medicine.
In these studies, the most common toremifene side effects included:
  • Hot flushes -- in up to 35 percent of women
  • Sweating -- up to 20 percent
  • Increases in certain liver enzymes (found using standard blood tests) -- up to 19 percent
  • Nausea -- up to 14 percent
  • Vaginal discharge -- up to 13 percent
  • Cataracts -- up to 10 percent
  • Dry eyes -- up to 9 percent
  • Dizziness -- up to 9 percent
  • Edema (swelling due to fluid retention) -- up to 5 percent
  • Vomiting -- up to 4 percent
  • Abnormal vision -- up to 4 percent
  • Increase in blood calcium levels (hypercalcemia) -- up to 3 percent
  • Vaginal bleeding -- up to 2 percent.

Final Thoughts

You may experience some or none of the side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
Therefore, make sure to let your healthcare provider know if you develop any adverse reactions while using the drug or if something "just does not seem right." While it may not be a side effect of toremifene, your healthcare provider will be able to diagnose and treat the problem.
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