Testicular Cancer Treatment by Stage (Cont.)

Stage II Testicular Cancer

Stage II testicular cancer treatment will depend on whether the cancer is a seminoma or a nonseminoma.
 
Treatment of seminoma for a tumor that is 5 centimeters or smaller may include:
 
  • Surgery to remove the testicle
  • Radiation therapy to lymph nodes in the abdomen and pelvis
  • Lifelong follow-up.
     
Treatment of seminoma for a tumor that is larger than 5 centimeters may include:
 
  • Surgery to remove the testicle.
  • Combination chemotherapy or radiation therapy to lymph nodes in the abdomen and pelvis
  • Lifelong follow-up.
     
Treatment of nonseminoma may include:
 
  • Surgery to remove the testicle and lymph nodes, with lifelong follow-up
     
  • Surgery to remove the testicle and lymph nodes, followed by combination chemotherapy and lifelong follow-up
     
  • Surgery to remove the testicle followed by combination chemotherapy and a second surgery if cancer remains, with lifelong follow-up
     
  • Combination chemotherapy before surgery to remove the testicle for cancer that has spread and is thought to be life-threatening.
     

Stage III Testicular Cancer

Treatment of stage III testicular cancer will depend on whether the cancer is seminoma or nonseminoma.
 
Treatment of seminoma may include:
 
  • Surgery to remove the testicle
  • Combination chemotherapy
  • Lifelong follow-up.
     
Treatment of nonseminoma may include:
 
  • Surgery to remove the testicle, followed by combination chemotherapy
     
  • Combination chemotherapy followed by surgery to remove any remaining tumor
     
  • Additional chemotherapy (if the tumor tissue removed contains cancer cells that are growing)
     
  • Combination chemotherapy combined with radiation therapy to the brain for cancer that has spread to the brain
     
  • Combination chemotherapy before surgery to remove the testicle for cancer that has spread and is thought to be life-threatening.
     
(Testicular Cancer Treatment by Stage Continued: Page 3)
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Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: Arthur Schoenstadt, MD