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Temodar Side Effects

Most people using Temodar will develop some type of side effect from the medicine. Some of the more commonly reported problems include hair loss, fatigue, and nausea. Because certain reactions can be quite serious, make sure you contact your healthcare provider right away if you are undergoing treatment with this drug and develop problems like seizures, unusual bleeding, or persistent vomiting.

An Introduction to Temodar Side Effects

As with any chemotherapy medicine, Temodar® (temozolomide) can cause side effects. In fact, most people will experience some type of reaction to this drug, and some side effects can be quite significant. Talk to your healthcare provider about ways to prevent or lessen reactions to this medicine.
(This article covers many, but not all, of the possible side effects with Temodar. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects With Temodar

Temodar has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people using Temodar were carefully documented. As a result, it was possible to see what side effects occurred and how often they appeared.
In these studies, the most common Temodar side effects included:
Other common side effects, occurring in 5 percent to 11 percent of people, included but were not limited to:
  • Swelling of the arms, hands, legs, ankles, or feet
  • Problems with coordination or movement
  • Viral infections
  • Problems with memory or memory loss
  • Insomnia
  • Mouth sores or ulcers (see Mouth and Gum Problems During Chemotherapy)
  • Blurred vision
  • Tingling, burning, pricking, or numbing sensations of the skin
  • Drowsiness
  • Abdominal (stomach) pain
  • Sore throat
  • Upper respiratory tract infection
  • Coughing
  • Back pain
  • Slight or partial paralysis
  • Urinary incontinence (loss of bladder control)
  • Increased urination
  • Urinary tract infection (UTI, such as a bladder infection)
  • Speech or communication difficulty
  • Overactive adrenal glands
  • Weakness
  • Anxiety
  • Depression
  • Sinus infection
  • Abnormal gait
  • Breast pain in females
  • Joint pain
  • An abnormal or unpleasant taste in the mouth
  • Muscle pain
  • Weight gain
  • Confusion
  • An allergic reaction
  • Shortness of breath
  • Red, itchy, or dry skin
  • Vision changes, such as problems with sight, blurred vision, or double vision.
The following side effects were reported in clinical trials of Temodar injections, in addition to the side effects listed above (however, the exact percentage of people experiencing the side effects were not listed in the Temodar prescribing information):
  • Bruising
  • Small red or purple spots under the skin
  • Pain, irritation, itching, warmth, swelling or redness at the site of infusion.
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Temodar Chemotherapy Information

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