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Temodar and Malignant Melanoma

People who have malignant melanoma may receive Temodar® (temozolomide). However, this is an "off-label," or unapproved, use of the medication. Temodar is a type of chemotherapy medicine that works by disrupting the replication process of DNA, preventing the cancer cells from growing and multiplying. It comes in the form of capsules or an injection that is given slowly into a vein (intravenous, or IV, infusion).
 
The approved uses of Temodar include treating certain brain tumors known as glioblastoma multiforme and anaplastic astrocytoma. It is approved only for use in adults, as it has not been adequately studied in children.
 
(Click Temodar Uses to learn more about off-label uses of this medication. This article also gives an overview of how the drug works.)
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