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Mechanism of Action of Romidepsin

Romidepsin (Istodax®) is a prescription medicine used to treat cancer that affects certain types of white blood cells called lymphocytes. Specifically, this drug is approved for use in people who have cutaneous or peripheral T-cell lymphoma and have already received at least one other treatment.
Romidepsin is a type of histone deacetylase (HDAC) inhibitor. However, its mechanism of action is not entirely understood. Romidepsin interferes with important proteins involved in gene expression -- the process by which the information contained in genes is interpreted. It may stop cancer cells from reproducing and cause cell death.
(To learn more about this drug's mechanism of action, click Romidepsin. This article covers several topics, such as potential side effects, dosing guidelines, and general safety precautions to discuss with your healthcare provider before beginning treatment.)
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