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Protein-Bound Paclitaxel

Protein-Bound Paclitaxel Effects

Previous studies have compared protein-bound paclitaxel with solvent-based paclitaxel that was used to treat metastatic breast cancer (cancer that has spread to other parts of the body). Up to 21.5 percent of people taking the protein-bound version showed improvement in their tumors, compared to just 11.1 percent of those taking solvent-based paclitaxel. Additionally, protein-bound paclitaxel injections were given over just 30 minutes, compared to 3 hours for solvent-based paclitaxel injections.
 
Similar results were seen in studies of protein-bound paclitaxel for non-small cell lung cancer, with more people responding to protein-bound paclitaxel, compared to solvent-based paclitaxel.
 
One study of protein-bound paclitaxel plus gemcitabine for pancreatic cancer showed that the addition of protein-bound paclitaxel helped improve survival, compared to gemcitabine alone.
 

When and How to Take Protein-Bound Paclitaxel

Some general considerations for when and how to take protein-bound paclitaxel include:
 
  • Protein-bound paclitaxel is given through an IV.
     
  • Most people receive their protein-bound paclitaxel injections at a healthcare provider's office, a hospital, or an "infusion center."
     
  • For the medication to work properly, it must be taken as prescribed. Protein-bound paclitaxel will not work as well if you stop taking it before your healthcare provider recommends.
     

Dosing Information for Protein-Bound Paclitaxel

The dose of protein-bound paclitaxel that your healthcare provider recommends will vary depending on a number of factors, including:
 
  • Your height and weight
  • The type of cancer
  • Other medications you may be taking
  • Other medical conditions you may have.
     
As always, do not adjust your dosage unless your healthcare provider specifically instructs you to do so.
 
(Click Protein-Bound Paclitaxel Dosing for more information.)
 
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Information on Protein-Bound Paclitaxel

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