Protein-bound paclitaxel (Abraxane^®) can potentially interact with certain other medications. Some of these medicines that may lead to protein-bound paclitaxel interactions include:

Certain antibiotics or antifungals, including:

Clarithromycin (Biaxin^®)
Erythromycin (Ery-Tab^®)
Isoniazid (Nydrazid^®)
Itraconazole (Sporanox^®)
Ketoconazole (Nizoral^®)
Miconazole
Telithromycin (Ketek^®)

Certain anticonvulsants, including:

Carbamazepine (Epitol^®, Equetro™, Tegretol^®, Tegretol XR^®)
Fosphenytoin (Cerebyx^®)
Oxcarbazepine (Trileptal^®)
Phenobarbital (Luminal^®)
Pentobarbital (Nembutal^®)
Phenytoin (Dilantin^®, Phenytek^®)
Primidone (Mysoline^®)

"Live" vaccinations, including:

Chickenpox vaccine (varicella vaccine)
FluMist^® (the nasal vaccine for influenza; the injected vaccine is not live)
MMR vaccine (measles, mumps, rubella vaccine)
Polio vaccine
Rotavirus vaccine
Smallpox vaccine
Yellow fever vaccine
BCG vaccine (used in some countries for tuberculosis)

Rifamycin antibiotics, including rifabutin (Mycobutin^®), rifampin (Rifadin^®), and rifapentine (Priftin^®).

Drug Interactions With Protein-Bound Paclitaxel Article Continues on Next Page >

Information on Protein-Bound Paclitaxel

List of references (click here)

Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD

Last reviewed by: Kristi Monson, PharmD

Protein-Bound Paclitaxel

Side Effects of Protein-Bound Paclitaxel

What Is Protein-Bound Paclitaxel Used For?

Protein-Bound Paclitaxel Dosing

Drug Interactions With Protein-Bound Paclitaxel

Precautions and Warnings With Protein-Bound Paclitaxel

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