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Drug Interactions With Protein-Bound Paclitaxel

Among the medicines that may potentially cause drug interactions with protein-bound paclitaxel are rifamycin antibiotics, certain anticonvulsants, "live" vaccinations, and certain antibiotics or antifungals. These protein-bound paclitaxel drug interactions may affect the levels of some medicines in your blood and increase your risk of developing side effects.

An Overview of Drug Interactions With Protein-Bound Paclitaxel

Protein-bound paclitaxel (Abraxane®) can potentially interact with certain other medications. Some of these medicines that may lead to protein-bound paclitaxel interactions include:
  • Certain antibiotics or antifungals, including:


    • Clarithromycin (Biaxin®)
    • Erythromycin (Ery-Tab®)
    • Isoniazid (Nydrazid®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Miconazole
    • Telithromycin (Ketek®)


  • Certain anticonvulsants, including:



  • "Live" vaccinations, including:



  • Rifamycin antibiotics, including rifabutin (Mycobutin®), rifampin (Rifadin®), and rifapentine (Priftin®).
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Information on Protein-Bound Paclitaxel

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