Drug Interactions With Protein-Bound Paclitaxel (Cont.)

Protein-Bound Paclitaxel Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when protein-bound paclitaxel is combined with any of the drugs listed above.
 
Certain Antibiotics or Antifungals
Combining certain antibiotics or antifungals with protein-bound paclitaxel may raise the level of protein-bound paclitaxel in your blood, increasing your risk of side effects. Talk with your healthcare provider before taking these medications together.
 
Certain Anticonvulsants
Combining protein-bound paclitaxel with certain anticonvulsants (seizure medications) can decrease the level of protein-bound paclitaxel in your blood, perhaps making it less effective. Talk with your healthcare provider before taking these medications together.
 
Live Vaccinations
Because chemotherapy (including protein-bound paclitaxel) can suppress the immune system, it is generally best to avoid live vaccinations while receiving chemotherapy.
 
Rifamycin Antibiotics
Combining protein-bound paclitaxel with rifamycin antibiotics can affect the level of protein-bound paclitaxel in your blood. Talk with your healthcare provider before taking these medications together.
 

Final Thoughts on Protein-Bound Paclitaxel Drug Interactions

It is possible that not all protein-bound paclitaxel drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions with protein-bound paclitaxel that may apply to you.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;