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Propoxyphene Napsylate Dosage

Propoxyphene Napsylate Dosing for Special Situations

If you are taking certain other medications known as CYP 3A4 inhibitors, you may need a lower propoxyphene napsylate dosage. These types of medications can slow the breakdown (metabolism) of propoxyphene napsylate by the liver (see Drug Interactions With Propoxyphene Napsylate).
If your kidney or liver function is not optimal, your healthcare provider may decide to prescribe a lower dose of propoxyphene napsylate. Similarly, lower amounts are often recommended for elderly individuals, who may be more sensitive to the effects of this medication.

General Information on Taking Propoxyphene Napsylate

Some considerations to keep in mind during treatment with propoxyphene napsylate include the following:
  • This medication comes in tablet form. It is taken by mouth every four hours as needed for pain. Do not ever take more than six tablets in 24 hours.
  • It is probably best to take a dose of propoxyphene napsylate with food, as it can be upsetting to the stomach.
  • Do not drink alcohol while taking this medication (see Darvon-N and Alcohol).
  • For this drug to work properly, it must be taken as prescribed. Do not increase your dose without your healthcare provider's approval. Do not suddenly stop taking propoxyphene napsylate, especially if you have taken it regularly for more than several weeks (see Darvon-N Withdrawal).
  • If you are unsure about anything related to your dosage or propoxyphene napsylate dosing in general, please talk with your doctor, nurse, or pharmacist. Do not stop taking the drug without first discussing it with your healthcare provider.
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Propoxyphene Napsylate Drug Information

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