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Pomalyst Dosage

Available in the form of capsules, Pomalyst is taken once a day to treat multiple myeloma. Pomalyst dosing guidelines normally call for 4 mg of the drug to be taken once a day for 21 days, followed by a 7-day break from taking the drug. This treatment cycle is repeated until the cancer progresses or serious side effects occur.

An Introduction to Dosing With Pomalyst

The dosage of Pomalyst® (pomalidomide) your healthcare provider recommends may vary, depending on how well you tolerate the medicine and whether you develop potentially serious Pomalyst side effects.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

What Is the Recommended Pomalyst Dosage?

The usual recommended initial dose of Pomalyst for treating multiple myeloma is 4 mg once daily for 21 days, followed by 7-day break when the medication is not taken. This 28-day cycle is usually repeated until the cancer progresses.
Your healthcare provider may recommend a temporary break in treatment if you experience certain potentially serious Pomalyst side effects, such as dangerously low blood cells. The medication is usually restarted at a lower dose once the side effect improves. If you continue to experience serious side effects at 1 mg a day, you may need to stop taking the medication altogether.
Some people will take Pomalyst with another medication known as dexamethasone (Decadron®, Dexpak®, Maxidex®). If your healthcare provider recommends this combination treatment, make sure you understand the instructions for taking dexamethasone as well.

General Information on Taking Pomalyst

Some considerations to keep in mind during treatment with Pomalyst include the following:
  • This medication comes in the form of a capsule. It is usually taken by mouth once a day.
  • Pomalyst should be taken without food, at least two hours before or two hours after a meal. You can use water to swallow the capsules.
  • Do not open, break, or chew Pomalyst capsules; they must be swallowed whole.
  • Take your dose of Pomalyst at the same time each day to keep an even level of the drug in your bloodstream.
  • Try not to handle the capsules any more than is necessary. If any of the medicine in the capsules gets on your hands or body, wash the area immediately with soap and water. 
  • Because Pomalyst can cause birth defects, women of childbearing potential must have a negative pregnancy test before starting treatment.
  • For the medication to work properly, it must be taken as prescribed. Do not stop taking it without first talking to your healthcare provider.
  • If you are unsure about anything related to your Pomalyst dosage, please talk with your healthcare provider, nurse, or pharmacist.
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