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Extramedullary Plasmacytoma
In extramedullary plasmacytoma, one plasma cell tumor is found in the soft tissue but not in the bone or the bone marrow.

How Is It Treated?

Treatment options for plasmacytoma vary based on the:
  • Stage of plasmacytoma
  • Symptoms of plasmacytoma
  • Person's age and general health.
In general, plasmacytoma treatment can include:
  • Radiation therapy
  • Chemotherapy
  • Surgery.
Patients should work with their doctors to develop a treatment plan that meets their medical needs and personal values. Choosing the most appropriate treatment is a decision that ideally involves the affected person, the family, and the healthcare team.
Isolated Plasmacytoma of Bone
Standard treatment of isolated plasmacytoma of bone usually involves radiation therapy.
Extramedullary Plasmacytoma
Standard treatment of extramedullary plasmacytoma may include:
  • Radiation therapy to the tumor and nearby lymph nodes
  • Surgery, usually followed by radiation therapy
  • Watchful waiting after initial treatment, followed by radiation therapy, surgery, or chemotherapy if the tumor grows or causes symptoms.

Prognosis With Plasmacytoma

The plasmacytoma prognosis will depend on:
  • The stage of plasmacytoma
  • Whether the cancer responds to initial treatment or recurs
  • The person's age and general health.
As mentioned, isolated plasmacytoma of the bone often becomes multiple myeloma. Extramedullary plasmacytomas commonly form in tissues of the throat and sinuses; these usually can be cured.
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