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Pentostatin

Pentostatin is a medicine prescribed to treat an uncommon cancer called hairy cell leukemia. As a type of chemotherapy drug, it works by interfering with the way cancer cells grow and multiply. This medication is injected into a vein once every other week. Most people develop some type of side effect during treatment, such as fatigue, nausea, or vomiting.

What Is Pentostatin?

Pentostatin (Nipent®) is a prescription medication approved to treat hairy cell leukemia, a rare type of blood and bone marrow cancer. This drug is approved for use as a single agent, which means it is used alone, not in combination with other chemotherapy medicines.
 
Pentostatin belongs to a group of medicines known as purine analogs. It may also sometimes be called 2-deoxycoformycin, or simply DCF.
 
(Click What Is Pentostatin Used For? for more information on this topic, including possible off-label uses.)
 

Are There Side Effects?

Just like any chemotherapy medicine, pentostatin can cause side effects, some of which can be significant and potentially serious. In fact, many people will experience some type of side effect during treatment. Talk with your healthcare provider about ways to prevent or lessen reactions to this drug.
 
Common side effects of pentostatin include but are not limited to:
 
  • Nausea and vomiting
  • Decrease in white blood cells
  • Fever
  • Rash
  • Fatigue
  • Infection.
 
(Click Pentostatin Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 
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Pentostatin Drug Information

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