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Pazopanib Side Effects

When taking pazopanib, side effects are possible and can include common reactions like headaches, nausea, and diarrhea. In many cases, these problems tend to be minor and easy to treat. However, some complications with this medicine may be potentially serious and require immediate medical treatment. Some of these problems include fainting, fever, or difficulty breathing.

An Introduction to Side Effects of Pazopanib

Just like any medicine, pazopanib (Votrient®) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible pazopanib side effects. Your healthcare provider can discuss a more complete list with you.)

Serious Pazopanib Side Effects

Some side effects of pazopanib are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling, especially of the mouth, lips, or throat
    • Wheezing
    • Difficulty breathing or swallowing
  • Signs of infection, such as:
  • Signs of liver problems, such as:
    • Yellowing of the skin or whites of the eyes (jaundice)
    • Dark urine
    • Tiredness or fatigue
    • Pain in the upper-right area of the abdomen (stomach)
  • High blood pressure (hypertension)
  • An irregular or rapidly beating heart
  • A slow heart rate
  • Dizziness or fainting
  • Chest pain or pressure
  • Pain in the arm, neck, back, or jaw
  • Shortness of breath
  • Vision or speech changes, weakness or numbness on one side of the body, or a severe headache
  • Unusual bleeding or bruising
  • Wounds that do not heal or appear infected
  • Black, tarry, or bloody stools
  • Vomiting blood or vomit that looks like coffee grounds
  • New or worsening abdominal (stomach) pain
  • Swelling in your hands, feet, or face
  • Severe diarrhea or diarrhea that does not go away
  • Signs of a serious condition known as reversible posterior leukoencephalopathy, including:
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Pazopanib Drug Information

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