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What Is Panitumumab Used For?

How Does It Work?

Panitumumab works by binding to a receptor in the body called epidermal growth factor receptor (EGFR). EGFR is found on the surface of normal cells and some cancer cells.
 
Normally, certain proteins, such as epidermal growth factor, bind to EGFR and tell cells to grow. By binding to EGFR, panitumumab blocks these proteins from binding and slows down the growth of cancer cells. Panitumumab does not cure cancer.
 

Can Children Use Panitumumab?

Panitumumab is not approved for use in children. Because the medicine has not been studied in children, it is unknown whether it is safe or effective in this age group. Talk with your child's healthcare provider about the particular benefits and risks of using this drug in children.
 

Is It Safe for Older Adults?

Older adults can use panitumumab. In clinical trials, older adults appeared to respond to and tolerate panitumumab the same as younger age groups. However, there were not enough older adults in the study to say for certain that this medication is safe and effective in older adults. In general, some older adults may be more sensitive to the side effects of this medication.
 

Are There Off-Label Reasons to Use Panitumumab?

On occasion, a healthcare provider may recommend this medicine for something other than the uses discussed in this article. This is called an "off-label" use. For example, panitumumab may be used off-label for the treatment of the following conditions:
 
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Panitumumab Drug Information

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