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Panitumumab and Colorectal Cancer

If you have colorectal cancer, panitumumab (Vectibix®) may help extend the time until the cancer progresses. However, this drug has not been shown to extend overall survival or improve cancer symptoms.
Colorectal cancer occurs when cancerous cells form in the tissue of the large intestine (colon) or rectum. Panitumumab is approved for use when colorectal cancer has spread beyond the colon or rectum to other parts of the body despite treatment with other chemotherapy treatments.
Panitumumab is only used in the treatment of cancer that has a certain protein, known as epidermal growth factor receptor (EGFR), on the surface of the cancer cells. This drug works by binding to EGFR, which slows down the growth of the cancer cells.
(For more information on using this drug to treat colorectal cancer, click What Is Panitumumab Used For?. This article also explains how this medication works, lists other possible uses, and talks about whether it is safe for use in children.)
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