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Drug Interactions With Oxymorphone ER

Barbiturates
Combining a barbiturate with oxymorphone ER can increase your risk for side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Talk to your healthcare provider before taking oxymorphone ER with a barbiturate.
 
Benzodiazepines
Taking oxymorphone ER in combination with a benzodiazepine might increase your risk for side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Talk to your healthcare provider before taking oxymorphone ER with a benzodiazepine.
 
Monoamine Oxidase Inhibitors (MAOIs)
Combining oxymorphone ER with an MAOI can cause serious reactions. Do not use oxymorphone ER and an MAOI within 14 days of each other.
 
Muscle Relaxants
Taking oxymorphone ER with a muscle relaxant may increase the risk for side effects. Check with your healthcare provider before combing oxymorphone ER with a muscle relaxant.
 
Other Narcotics or Opiates
Use extreme caution when combining oxymorphone ER with other narcotics or opiates, as serious side effects could occur. You should only use these medications together with your healthcare provider's approval and supervision.
 
Sleep Medications
Oxymorphone ER can cause significant drowsiness, and combining it with a sleep medication could lead to dangerous effects. In general, oxymorphone ER should not be used in combination with sleep medications, unless your healthcare provider specifically tells you to do so.
 

Final Thoughts

It is possible that not all oxymorphone ER drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific interactions that may apply to you.
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