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Oxaliplatin Neuropathy

Although oxaliplatin (Eloxatin®) can be an effective chemotherapy treatment for certain types of colon or rectal cancer, this drug has the potential to cause nerve damage in the body. In fact, a majority of people who undergo treatment with oxaliplatin will develop some type of neuropathy (nerve problem). There are two types of neuropathy associated with this chemotherapy treatment: acute (short-duration) neuropathy and persistent (longer-duration) neuropathy.
The acute form can occur within hours of receiving an oxaliplatin infusion, or up to a couple of days after the infusion is given. This type of neuropathy usually goes away within 14 days. Some of these short-term neuropathy symptoms include:
  • Jaw tightness
  • Difficulty speaking
  • Eye pain.
Persistent neuropathy is characterized by nerve problems that continue for longer than 14 days. Symptoms may include:
  • Numbness
  • Tingling
  • Burning sensations in the hands, feet, throat, or around your mouth.
(For more information on these types of neuropathy, click Nerve Problems With Eloxatin. This resource further explores nerve problems associated with this drug, and offers some tips on how to cope with these symptoms.)
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