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Omacetaxine Side Effects

Common Side Effects

Omacetaxine has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people given the drug were carefully documented. As a result, it was possible to see what side effects occurred and how often they appeared.
In these studies, the most common omacetaxine side effects included:
  • A low number of platelets in the blood (see Blood Clotting Problems and Chemotherapy) -- in up to 74 percent of people
  • Anemia (see Chemotherapy and Anemia) -- up to 61 percent
  • An infection of any kind, including bacterial, viral, and fungal infections -- up to 56 percent
  • A low level of neutrophils (a type of white blood cell) in the blood (see Chemotherapy and Infections) -- up to 50 percent
  • Diarrhea -- up to 42 percent
  • Reactions at the injection site, such as redness, pain, or irritation -- up to 34 percent
  • Nausea (see Chemotherapy and Nausea) -- up to 32 percent
  • Fatigue -- up to 31 percent
  • Fever -- up to 29 percent
  • Loss of strength and energy -- up to 24 percent.
Other common reactions, occurring in 10 percent to 19 percent of people, included:
  • Joint pain
  • Headache
  • A low level of lymphocytes (another type of white blood cell)
  • Cough
  • Nosebleeds
  • Hair loss (see Chemotherapy and Hair Loss)
  • Constipation
  • Vomiting
  • Upper abdominal (stomach) pain
  • Chills
  • Swelling of the arms, hands, legs, and feet
  • Arm and leg pain
  • Loss of appetite
  • Back pain
  • Shortness of breath
  • Insomnia
  • Rash
  • Bone marrow failure (an inability of the bone marrow to make blood cells).
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Omacetaxine Mepesuccinate Information

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