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Omacetaxine

How Does It Work?

It is not entirely known how omacetaxine works. One of the ways it is thought to work is by blocking the production of certain proteins that stimulate the development of the abnormal blood cells found in leukemia. Interestingly, omacetaxine is made from the leaves of an evergreen tree (Cephalotaxus sp., more commonly known as the Cowtail Pine or Japanese Plum Yew).
 

When and How to Use This Medicine

Some general considerations to keep in mind during treatment with omacetaxine include the following:
 
  • This medicine comes as a powder that is dissolved in liquid and given as an injection just under the skin (a subcutaneous injection). The injections are normally given twice a day for 7 to 14 days in a row, followed by a break in treatment.
 
  • Omacetaxine doses are usually given by a healthcare provider in a healthcare facility, such as a hospital or infusion center.
 
  • This medication can irritate the skin. Avoid getting it on your skin. If contact does occur, wash the area thoroughly with soap and water.
 
  • Omacetaxine vials should be inspected before use, and should not be used if the medicine contains particles or is discolored.
 
  • For this drug to work properly, it must be used as prescribed. It works best if taken on schedule. However, you may need to miss a dose due to side effects.
 

Dosing Information for Omacetaxine

The dose of omacetaxine your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • Your height and weight
  • How you respond to the medication
  • How you tolerate it, such as if you experience certain side effects.
 
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
 
(Click Omacetaxine Dosage for more information.)
 
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