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Omacetaxine

Important Information for Your Healthcare Provider

Talk with your healthcare provider prior to receiving this medication if you have:
 
  • An infection of any kind
  • Low white blood cell counts
  • Diabetes or high blood sugar (blood glucose) levels
  • Any allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
   
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
(Click Precautions and Warnings With Omacetaxine to learn more, including information on who should not use the drug.)
 

Clinical Effects of Omacetaxine

Omacetaxine was studied in clinical trials that included people with CML who had previously been treated with at least two tyrosine kinase inhibitors but did not tolerate the medications or did not adequately respond to them. In these studies, 18.4 percent of people with chronic-phase CML, on average, had a major cytogenetic response, meaning 35 percent or less of cells tested positive for the Philadelphia chromosome (a genetic abnormality found in most people with CML).
 
It took a median of 3.5 months for this reduction in leukemia cells to occur (the median is the middle number, meaning half of the people responded within 3.5 months, while the other half took longer than 3.5 months). The reduction in leukemia cells lasted a median of 12.5 months.
 
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Omacetaxine Mepesuccinate Information

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