Precautions and Warnings With Nilotinib

To help minimize risks while using nilotinib, tell your healthcare provider if you have a history of pancreatitis, heart problems, or liver disease. It is also important for your healthcare provider to know about any other medications, vitamins, or supplements you are taking to avoid potentially serious drug interactions with nilotinib. Other warnings and safety precautions apply to women who are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider Before Taking Nilotinib?

You should talk with your healthcare provider prior to taking
 nilotinib (Tasigna®) if you have:
 
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • An irregular heartbeat
  • A heart condition known as QT prolongation or long QT syndrome
  • Heart disease, such as congestive heart failure
  • A history of pancreatitis (inflammation of the pancreas)
  • Been told you have low blood magnesium or potassium levels (hypomagnesemia or hypokalemia)
  • A lactose intolerance (an inability to digest dairy products)
  • Had surgery to remove your stomach (called a total gastrectomy)
  • Any allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
 
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
Precautions and Warnings With Nilotinib Article Continues on Next Page >
Written by/reviewed by: Susan Lakey, PharmD, MPH, BCPP
Last reviewed by: Kristi Monson, PharmD
 
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