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Neupogen Uses

How Does Neupogen Work?

Neupogen belongs to a group of medications called granulocyte colony-stimulating factors. Colony-stimulating factors bind to stem cells in the bone marrow, stimulating the production of blood cells. Granulocyte colony-stimulating factor (G-CSF) is a naturally occurring chemical in the body that stimulates the production of neutrophils. Neupogen is a synthetic version of G-CSF. Neupogen binds to stem cells and stimulates the production of neutrophils, helping to decrease the risk of infection.

Neupogen Uses in Children

Neupogen is approved for use in children, particularly for children with severe chronic neutropenia. Because some children who were being treated with Neupogen long-term have developed leukemia, it is possible that Neupogen may increase the risk of leukemia in children. Talk to your healthcare provider about the benefits and risks of using Neupogen in children.

Off-Label Neupogen Uses

On occasion, your healthcare provider may recommend Neupogen for something other than for the uses discussed in this article. At this time, there are no universally accepted off-label Neupogen uses. However, some off-label uses of Neupogen include the treatment of:
  • Neutropenia caused by non-chemotherapy medications
  • Aplastic anemia (a severe form of anemia that affects white blood cells, red blood cells, and platelets).
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