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Mutamycin Drug Interactions

Mutamycin Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Mutamycin is combined with any of the drugs listed above.
 
Amphotericin B
Combining amphotericin B with certain chemotherapy medicines, such as Mutamycin, may increase the risk for amphotericin B side effects, including kidney damage, low blood pressure (hypotension), and lung problems. Your healthcare provider may choose to monitor you more closely for side effects if you use these medicines together.
 
Certain Biologic and Immunologic Medications
People who are treated with Mutamycin in combination with certain other medicines that suppress the immune system may have a higher risk for side effects, especially infections. It is recommended that Mutamycin not be used in combination with some biologic and immunologic medicines, while other combinations will require close monitoring.
 
Clozapine
Taking clozapine with Mutamycin may increase the risk for dangerously low white blood cells and potentially serious infections. It is generally recommended that these medicines not be used together. However, do not stop taking clozapine unless your healthcare provider specifically tells you to do so.
 
Echinacea
Echinacea may decrease the effectiveness of Mutamycin. Check with your healthcare provider before taking these products together.
 
Live Vaccinations
Live vaccines contain live viruses or bacteria. If you receive a live vaccine during Mutamycin treatment, you might become infected with the virus or bacteria used to make the vaccine.
 
In addition, live vaccines may be less effective in people receiving Mutamycin. In general, people receiving chemotherapy are advised to not get live vaccinations. Talk to your healthcare provider before receiving a vaccination or immunization during Mutamycin treatment and for three months after your last dose.
 
P-glycoprotein (Pgp) Inducers
P-glycoprotein is a protein found in the body. One of its roles is to help remove substances, such as medications, from the tissues of the body so they can be removed through the urine or feces. Pgp helps remove Mutamycin from the body. Certain other medications, known as Pgp inducers, increase the activity of Pgp.
 
Taking Mutamycin with one of these drugs may cause Mutamycin to be removed from the body too quickly, potentially making it less effective. Your healthcare provider may choose to monitor you more closely if you use these drugs together.
 
P-glycoprotein (Pgp) Inhibitors
P-glycoprotein is a protein found in the body. One of its roles is to help remove substances, such as medications, from the tissues of the body so they can be excreted through the urine or feces. Pgp helps remove Mutamycin from the body. Certain other medications, known as Pgp inhibitors, decrease the activity of Pgp.
 
Taking Mutamycin with one of these drugs may cause Mutamycin to be removed more slowly, potentially increasing the amount of Mutamycin in your body, as well as your risk for side effects. Your healthcare provider may choose to monitor you more closely if you use these medications together.
 
Roflumilast
Combining roflumilast with Mutamycin may further increase your risk for developing infections. Talk to your healthcare provider about this potential interaction before using these drugs together.
 
Sipuleucel-T
Mutamycin may decrease the effectiveness of sipuleucel-T. This is because sipuleucel-T works by stimulating the body's immune system, while Mutamycin decreases the activity of the immune system. Talk to your healthcare provider about this possible interaction before using these medicines together.
 
Vinca Alkaloids
Breathing problems have been reported in people taking a vinca alkaloid anticancer medicine in combination with Mutamycin or after treatment. Your healthcare provider will carefully monitor you for signs of lung problems, such as shortness of breath or difficulty breathing, if you receive a vinca alkaloid in addition to Mutamycin.
 
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