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Mutamycin Dosage

Your healthcare provider will calculate your Mutamycin dosage based on your height, how much you weigh, how you tolerate the medication, and other factors. Mutamycin comes as a powder that is dissolved in sterile water to form a liquid, which is then injected into a vein. This chemotherapy drug is usually given once every six to eight weeks.

An Introduction to Dosing With Mutamycin

The dose of Mutamycin® (mitomycin) your healthcare provider recommends may vary, depending on several factors, such as:
  • Your height and weight
  • How you respond to and tolerate the medication
  • Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

What Is the Recommended Mutamycin Dosage?

Like many chemotherapy drugs, Mutamycin doses are based on body surface area, which is calculated using your height and weight. Doses based on body surface area are written as milligrams per meter squared (mg per m2).
The usual recommended amount of Mutamycin for the treatment of stomach or pancreatic cancer is 10 to 20 mg per m2. People with liver or kidney disease may be treated with lower dosages. The drug is usually given every six to eight weeks, depending on the number of white blood cells and platelets in your body.
Mutamycin causes myelosuppression (a decrease in the ability of the bone marrow to make blood cells). Your healthcare provider will monitor your blood cell counts after each dose, and adjust your next dose based on how low your blood cell counts drop at their lowest level (called the nadir). You will not receive further doses until your platelets and white blood cell counts return to a normal level.
Your healthcare provider may stop treatment with Mutamycin if your cancer continues to progress after two dosages. People who do not adequately respond to two doses of Mutamycin are unlikely to gain additional benefit.
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Mutamycin Drug Information

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