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Morphine Sulfate ER Warnings and Precautions

Specific Morphine Sulfate ER Warnings and Precautions

Some warnings and precautions to be aware of prior to taking morphine sulfate ER include the following:
  • Morphine sulfate ER tablets and capsules are designed to release morphine slowly over time. Do not dissolve, chew, or crush the tablets, as this could cause an overdose.
  • Morphine sulfate ER is a narcotic medication with significant potential for abuse. It is a long-acting version of morphine. It is not a good choice for people who have a history of alcohol or drug abuse. Do not take the drug more frequently, longer, or at a higher dose than prescribed. If you feel you may be developing a problem with morphine sulfate ER, please seek help from your healthcare provider.
  • The medication can cause problems in people with head injuries or high intracranial pressure. Morphine sulfate ER should only be used with extreme caution in such circumstances.
  • Morphine sulfate ER can cause slow and irregular breathing, especially at high doses. In severe situations, this may cause life-threatening complications. This may be especially dangerous in people with lung problems.
  • Morphine sulfate ER can cause a decrease in blood pressure, which can be especially dangerous if you already have low blood pressure or are prone to low blood pressure. Let your healthcare provider know if you experience signs of low blood pressure, such as lightheadedness, dizziness, or fainting.
  • Narcotics such as morphine sulfate ER are likely to cause constipation. This side effect does not go away as you continue to take the drug. Usually, laxatives are necessary to treat and prevent constipation due to morphine sulfate ER. Let your healthcare provider know if you develop severe constipation, as this could be a sign of an intestinal blockage.
  • Morphine sulfate ER can interfere with the diagnosis of many conditions that cause severe abdominal (stomach) pain.
  • Like any other narcotic, morphine sulfate ER can cause dizziness and drowsiness, and may increase the risk of falls in elderly people.
  • Do not drive or operate heavy machinery until you know how morphine sulfate ER affects you. Your reflexes and reaction times may be significantly affected, even if you feel fine.
  • Check with your healthcare provider before taking the drug if you have hypothyroidism, Addison's disease, an enlarged prostate, epilepsy, gallbladder problems, pancreatic disease, or kidney disease, as morphine sulfate ER may not be the best choice for you.
  • Morphine sulfate ER can potentially interact with several other medications (see Drug Interactions With Morphine Sulfate ER).
  • Morphine sulfate ER is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not known (see Avinza and Pregnancy, Kadian and Pregnancy, MS Contin and Pregnancy, or Oramorph and Pregnancy).
  • Morphine sulfate ER passes through breast milk. Therefore, if you are breastfeeding or plan to start breastfeeding, discuss this with your healthcare provider prior to taking the drug (see Avinza and Breastfeeding, Kadian and Breastfeeding, MS Contin and Breastfeeding, or Oramorph and Breastfeeding).
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Morphine Sulfate ER Medication

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