Indications for Marinol

The U.
 S. Food and Drug Administration (FDA) has approved Marinol® (dronabinol) for the following indications (uses):
 
  • Appetite loss (known medically as anorexia) associated with weight loss in people with AIDS (acquired immunodeficiency syndrome)
  • Nausea and vomiting from cancer chemotherapy, when other treatments have not worked.
     
This medication is believed to work by binding to certain receptors in the central nervous system. In clinical studies, the combination of Marinol and prochlorperazine (Compazine®) was shown to reduce chemotherapy-induced nausea and vomiting more than the use of prochlorperazine alone.
 
Marinol comes in the form of a capsule, and is taken anywhere from two to six times a day, depending on the condition being treated, side effects, and other factors.
 
(Click Marinol Uses to learn more about when this medication is indicated as a treatment for nausea, vomiting, and appetite loss. This article explains in more detail how Marinol works and whether children can take it.)
 
Written by/reviewed by: Susan Lakey, PharmD, MPH
Last reviewed by: Kristi Monson, PharmD