Cancer Home > Zuplenz Dosage

Your healthcare provider will take several factors into consideration before prescribing a specific Zuplenz dosage. Some of these factors include your age, the medical condition being treated, and other medications you are taking. This prescription medication comes in the form of a small film that dissolves on the tongue within 4 to 20 seconds.

An Introduction to Dosing With Zuplenz

The dose of Zuplenz™ (Ondansetron Oral Soluble Film) your healthcare provider recommends will vary depending on a number of factors, including:
 
  • Your age
  • The medical condition being treated
  • Other medical conditions you may have
  • Other medications you are taking.
     
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
 

Zuplenz Dosage for After Surgery

The dosage of Zuplenz for preventing postoperative nausea and vomiting is 16 mg (two 8-mg films) taken one hour before anesthesia is administered.
 

Zuplenz Dosage for Chemotherapy

The dose of Zuplenz depends on the type of chemotherapy and how likely it is to cause nausea and vomiting, as follows:
 
  • High-risk chemotherapy: The Zuplenz dose for high-risk chemotherapy is 24 mg (taken as three 8-mg films) 30 minutes before chemotherapy.
     
  • Medium-risk chemotherapy: The dosage of Zuplenz for medium-risk chemotherapy is 8 mg twice daily. The first dose should be taken 30 minutes before chemotherapy, and the second one should be taken eight hours after the first one. After that, Zuplenz should be taken twice a day (about every 12 hours) until one to two days after chemotherapy.
     
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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