Cancer Home > Zortress Side Effects
Nausea, constipation, and increased blood pressure are some of the most commonly reported side effects of Zortress. While reactions such as these are typically minor, there are some potentially dangerous side effects that require medical treatment. Contact your healthcare provider right away if you develop chest pain, blurred vision, blood in your urine, or other potentially serious problems.
An Introduction to Zortress Side EffectsJust like any medicine, Zortress® (everolimus) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Zortress. Your healthcare provider can discuss a more complete list with you.)
Common Side Effects of Zortress
Zortress has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking Zortress plus other anti-rejection medications were documented and then compared to the side effects that occurred in a similar group of people taking just the other anti-rejection medications without Zortress.
As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the other medicine. In these studies, the most common Zortress side effects included:
- Swelling of the legs, ankles, and feet -- in up to 45 percent of people
- Constipation -- up to 38 percent
- Increased blood pressure (hypertension) -- up to 30 percent
- Nausea -- up to 29 percent
- Anemia (decreased red blood cell count) -- up to 26 percent
- Urinary tract infection (UTI) -- up to 22 percent
- Increased lipids in the blood (high cholesterol and triglycerides) -- up to 21 percent
- Diarrhea -- up to 19 percent
- Fever -- up to 19 percent
- Headaches -- up to 18 percent
- Increases or decreases in blood potassium levels -- up to 18 percent
- Insomnia -- up to 17 percent.
Other common side effects, occurring in 3 to 16 percent of people, included:
- Upper respiratory tract infections (such as the common cold)
- Pain at the incision site (the surgical cut)
- Low levels of certain blood electrolytes (magnesium and phosphorus)
- Abdominal (stomach) pain
- High blood sugar (high glucose levels)
- Blood in the urine
- Painful urination
- Pain, including back pain and pain in the arms and legs
- Ulcers or sores in the mouth
- Heartburn or indigestion
- Low white blood cell count.