Cancer Home > Vismodegib

Vismodegib is a drug given to treat certain situations where basal cell carcinoma has come back after surgery or the cancer has spread to other areas. It is also prescribed when surgery or radiation is not an option. The drug comes in the form of capsules that are taken once a day. Fatigue, nausea, and hair loss are possible side effects.

What Is Vismodegib?

Vismodegib (Erivedge™) is a prescription medication licensed for the treatment of basal cell carcinoma, the most common type of skin cancer. It is specifically approved for use when:
  • The cancer has come back after surgery
  • Surgery or radiation is not an option
  • The cancer has spread to other parts of the body (metastasized).
Vismodegib is the first drug approved for metastatic basal cell carcinoma.
(Click What Is Vismodegib Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, vismodegib can cause side effects, some of which may be significant. Although not everyone who takes the drug will experience problems, most people will have some type of side effect during treatment.
Some of the most common adverse reactions seen with this medication include but are not limited to:
  • Muscle spasms
  • Hair loss
  • Altered sense of taste
  • Weight loss
  • Fatigue
  • Nausea.
(Click Vismodegib Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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