Cancer Home > Vinorelbine

People who have non-small cell lung cancer may receive a chemotherapy drug called vinorelbine. This prescription medicine is derived from the Madagascar periwinkle plant, and works by preventing cancer cells from growing and dividing. It is given as an injection into a vein once a week. Side effects are common with this product and may include loss of energy, nausea, and anemia.

What Is Vinorelbine?

Vinorelbine (Navelbine®) is a prescription medication approved to treat a type of lung cancer known as non-small cell lung cancer. It may be used alone or in combination with another chemotherapy medicine called cisplatin (Platinol®).
 
Vinorelbine contains the active ingredient vinorelbine tartrate, or simply vinorelbine. This drug belongs to a general class of chemotherapy medicines called plant alkaloids. There are several types of plant alkaloids, and vinorelbine is a vinca alkaloid. Vinca alkaloids are anticancer medicines derived from the Madagascar periwinkle plant (Catharanthus roseus).
 
(Click What Is Vinorelbine Used For? for more information on this topic, including possible off-label uses.)
 

Are There Side Effects?

Just like any chemotherapy medicine, vinorelbine can cause side effects, some of which can be significant and potentially serious. In fact, most people will experience some type of side effect during vinorelbine treatment. Talk with your healthcare provider about ways to prevent or lessen reactions to this drug.
 
Common side effects of vinorelbine include but are not limited to:
 
  • A decrease in white blood cells
  • Anemia
  • An increase in certain liver enzymes
  • Nausea
  • Loss of strength and energy.
 
(Click Vinorelbine Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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