Cancer Home > Vemurafenib

Vemurafenib is a medicine that may be prescribed when melanoma (a type of skin cancer) has spread to other areas of the body or cannot be treated with surgery. This drug is specifically used in people who have an abnormal gene which causes abnormal cell growth. The tablets are taken twice daily. Joint pain, fatigue, and a rash are possible side effects.

What Is Vemurafenib?

Vemurafenib (Zelboraf™) is a prescription medication approved to treat melanoma (a type of skin cancer) that cannot be treated with surgery or has spread to other areas of the body (metastasized). It is meant for use in people who have an abnormal BRAF V600E gene.
(Click What Is Vemurafenib Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, vemurafenib can cause side effects. Although not everyone who takes the drug will have problems, most people will experience some type of side effect during treatment.
If reactions do occur, in most cases, they are mild or moderate in severity and either require no treatment or can be treated by you or your healthcare provider. Serious side effects are less common.
Common side effects of vemurafenib include but are not limited to:
  • Joint pain
  • A rash
  • Hair loss
  • Fatigue
  • Sun sensitivity.
(Click Vemurafenib Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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