Cancer Home > Precautions and Warnings With Vemurafenib

To help avoid complications while taking vemurafenib, your healthcare provider needs to know your medical history and have a list of all medications, vitamins, and supplements you are taking. This prescription medicine can increase the risk for some people to develop heart rhythm problems, liver disease, or severe allergic reactions. Other warnings and safety precautions with vemurafenib apply to women who are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider Before Taking Vemurafenib?

You should talk with your healthcare provider prior to taking vemurafenib (Zelboraf™) if you have:
 
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Kidney disease, such as kidney failure
  • A history of skin cancer
  • Frequent sun exposure
  • An irregular heartbeat
  • A heart condition known as QT prolongation or long QT syndrome
  • Been told you have low blood electrolytes, such as low blood magnesium, calcium, or potassium levels
  • Eye problems, including eye conditions known as uveitis or iritis
  • Any allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
 
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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