Cancer Home > Triptorelin Side Effects

Hot flashes, bone pain, and flu-like symptoms are some of the commonly reported side effects of triptorelin. Most people tolerate this medication well, but serious reactions -- although rare -- are also possible, including chest pain, dizziness, and mood swings. To help ensure your safety, contact your healthcare provider if you develop any possible side effects while using this medicine.

An Introduction to Triptorelin Side Effects

Just like any medicine, triptorelin pamoate (Trelstar®) can cause side effects. However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with triptorelin. Your healthcare provider can discuss a more complete list with you.)

Serious Side Effects of Triptorelin

Some triptorelin side effects are potentially serious and should be reported immediately to your healthcare provider. These include:
  • Blood in the urine or difficulty urinating
  • Persistent or extreme bone pain, joint pain, or body pain
  • High blood pressure (hypertension)
  • Chest pain (angina)
  • Signs of a stroke, such as:
    • A sudden, severe headache
    • Numbness or weakness of the face, arm, or leg, especially on one side of the body
    • Confusion
    • Slurred speech
    • Vision problems
  • Signs of a blood clot, such as:
    • Severe pain
    • Swelling
    • Weakness
    • Numbness of an arm or leg
  • Signs of a blood clot in the lung, such as:
    • Shortness of breath
    • Sudden chest pain
    • Coughing up blood
  • Signs of anemia, such as:
    • Fatigue
    • Pale skin
    • Dizziness
    • Shortness of breath
  • A fast or irregularly beating heart
  • Mood changes, such as depression, anxiety, or mood swings
  • Severe reactions at the injection site, such as extreme redness, pain, pus, or bleeding
  • Swelling of the hands, ankles, legs, or feet
  • Yellowing of the skin or whites of the eyes (jaundice)
  • Changes in blood sugar or signs of diabetes, such as:
    • Frequent urination
    • Increased thirst
    • Blurred vision
    • Fatigue
    • Weight loss
  • Signs of pituitary apoplexy (a stroke of the pituitary gland) such as:
    • Sudden, severe headache
    • Inability to move your eyes
    • Blurred vision
    • Nausea and vomiting
    • Low blood pressure
    • Confusion
  • Signs of an allergic reaction, such as:
    • Hives
    • Itching
    • Unexplained swelling of the mouth or throat
    • Wheezing or difficulty breathing or swallowing.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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