At this time, you cannot buy generic Trexall. Even though there are no unexpired patents for the medication, no manufacturers have decided to go ahead with the production of a generic version. It's important to note that many people consider generic methotrexate tablets equivalent to Trexall. However, you would have to take more of the methotrexate tablets to get an equivalent dose.
Currently, brand-name Trexall is made by Teva Pharmaceuticals, Inc. There are no generic versions of Trexall available at this time, although lower strengths of generic methotrexate tablets are available.
When Will Generic Trexall Be Available?
This is a difficult question to answer. Although there are no unexpired patents that protect Trexall from generic competition, no manufacturers have chosen to make generic Trexall. As soon as a generic manufacturer decides to produce such a medication and receives approval from the U.S. Food and Drug Administration (FDA), generic Trexall could become available.
Is Generic Methotrexate Equivalent to Trexall?
Trexall comes in 5-mg, 7.5-mg, 10-mg, and 15-mg tablets. Generic methotrexate 2.5-mg tablets are technically not equivalent to or interchangeable with Trexall. However, it is important to understand that Trexall was approved based on the fact that it was simply a higher strength of the already-approved 2.5-mg methotrexate tablets.
So, for practical purposes, most people would consider generic methotrexate equivalent to Trexall, except that the strengths are different. Depending on your particular pharmacy and your particular insurance plan, you may find that the generic methotrexate tablets are less expensive, even though you need to take more of them for an equivalent dose.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Methotrexate [package insert]. Lake Forest, IL: Hospira, Inc.;2011 October.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed December 3, 2009.
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